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The ADVIA® 120 Hematology System - Gets The Job Done

The ADVIA® 120 Hematology System from Bayer Diagnostics gets the job done and gets it right the first time, with a review rate far lower than competing systems. Results are more accurate, physicians are more confident and treatment is more effective. The ADVIA 120 Hematology System, for great performance, the one and only.

Advancing world standards in hematology

Improve your service to clinicians and patients with the ADVIA® 120 Hematology System. A system that is designed to streamline laboratory workflow and achieve long-term economic benefits…a system you can always rely on to get the right results the first time. This simple benchtop analyzer offers a unique portfolio of diagnostic assays, meeting the needs of clinicians, enhancing patient management and adding value to your laboratory.

Elevates your standards

The ADVIA 120 system features patented, proprietary clinical parameters - raising the level of care your physicians can provide.


•	Benefit from technology which utilizes Peroxidase staining - the gold standard for differential testing.
•	Detect abnormalities early and differentiate leukemias with cytochemical staining and nuclear complexity.
•	Maximize the effectiveness of costly platelet transfusions with accurate results the first time, every time - even at very low platelet levels.
•	Achieve sensitive detection of red cell abnormalities without recourse to expensive and time - consuming manual tests.
•	Differentiate microcytic anemias (thalassemia, iron deficiency) and macrocytic anemias (hereditary spherocytosis, sickle cell) with RBC and reticulocyte technology.
•	Detect and treat iron deficiency anemia using CHr™. %Hypo assay* maybe a useful tool in the investigation of iron deficiency.

*%Hypo™ assay is for research use only, not for use in diagnostic procedures in the US. The CHr assay has been cleared by the FDA. Both tests are available only on the Bayer Hematology systems.

Really means business


•	Use of the ADVIA 120 Hematology System enables you to achieve immediate workflow efficiencies. This enhances patient care by facilitating the path to diagnosis, while freeing skilled laboratory staff for other tasks.
•	Rack-based capacity for 150 samples delivers all the benefits of "walkaway" convenience.
•	Fixed throughput of CBC/Diff at 120 samples per hour, even on leukopenic samples, provides fast results reporting to enhance the service to clinicians.
•	Accurate results on all samples whether immediately post-collection or up to 54 hours old reduce the need for retesting.
•	Increased linearities minimize costly, timeconsuming dilutions and repeats.
•	Proven technology, reference methods and onboard delta checks reduce manual slide reviews.
•	Internal QC checks on every sample allow results to be reported with confidence, as anomalous results are highlighted automatically.

Saves for the future.


•	Supplies, equipment, staffing: On every front, the ADVIA 120 Hematology System helps you reallocate resources, reduce costs – and deliver better results.
•	Cross-train operators easily on intuitive software, minimizing the need for dedicated staff.
•	Select only the tests the physician orders.
•	Eliminate separate reticulocyte analyzer – workstation has fully automated random-access reticulocytes; no batching is required.
•	Right results the first time saves unnecessary reagent usage, reduces film review rates and minimizes the need for time-consuming repeats.

Makes the difference. Peroxidase staining, the gold standard for differential testing. WBC identification, based on cytochemical light scatter and light absorption measurements.

Knows anemia. Comprehensive parameters for anemia support disease management, shorten time to diagnosis. CHr assay delivers a snapshot assessment, contributes to optimization of EPO and iron therapy.

Exceeds your expectations. CSF Assay: Automated WBC, RBC, differential, PMN and MN results in less than 1 minute from aspiration.

Optional MultiSpecies Software: 21 species-specific algorithms ensures accuracy of results. Comprehensive software allows for 30 additional user-definable species.

Configures to Your Need

ADVIA 120 software boasts a simplified user interface - customizable to your needs. Comprehensive information management - from patient results to QC. And proactive servicing - for 24-hour operation.


•	User-defined screen configurations and reports correspond to your institution’s use models.
•	Onboard diagnostics - and ADVIA e-Service remote monitoring capabilities - support quick troubleshooting and increase reliability.
•	Memory stores up to 10,000 patient results, including graphics.

Facilitate rapid diagnosis with online, context-sensitive help.

Delivers value in every detail.

The ADVIA 120 is designed to meet real life user needs: comprehensive testing parameters, flexible sample handling, customer-designed user interface with multi-tasking, compact benchtop design. Extensive linearity range, sensitive and specific result flagging, cross-checking WBC technologies and dual hemoglobin readings combine to minimize review rates and repeats.

Bar-coded data entry decreases transcription errors, simplifies reagent tracking and ordering.

Maximizes workflow efficiency.

Rapid turnaround of accurate results is achieved through:


•	Fast, convenient, rack-based sampling
•	High throughput of 120 samples per hour
•	Results which are right the first time
•	Minimal manual review
•	Efficient auto-validation procedures

Rack-based sampler accommodates 150 samples in multiple tube sizes.

Keeps the Laboratory Productive - Around The Clock


1.	Unique Unifluidics™ technology at the heart of the system streamlines components, simplifies operation and reduces maintenance by eliminating pinch valves and tubing.
2.	Reagents: compact bar-coded reagents onboard; each pack contains sufficient reagent for 1,850 tests.
3.	Rack-based auto-sampler with capacity of 150 tubes provides 75 minutes of true “walkaway” time, maximizing laboratory productivity.
4.	Unique Manual Closed Tube Sampling (MCTS) mode, ideal for high risk/urgent samples, while Manual Open Tube Sampling (OTS) facility accommodates small samples. The third sampling option – rack-based auto-sampling – ensures maximum flexibility.
5.	Manual bar-code reader makes it easy to input data for STAT samples, QC material and reagents, and ensures accuracy of data.
6.	Fast, one-button startup is simple and easy to use for staff at all levels.

Product specifications

Performance Specifications

WBC	0.02 to 400 x 10³/µL
RBC	0.0 to 7.0 x 10⁶/µL
PLT	5.0 to 3500 x 10³/µL
HB	0.0 to 22.5 g/dL
Retic	0.2 to 24.5%

Precision

Parameter	Mean	SD	CV
WBC	7.5	0.20	2.7
RBC	5.0	0.06	1.2
HB	15.0	0.14	0.93
MCV	90.0	0.7	0.78
PLT	300.0	8.8	2.93
Retic%	2.0	0.25	12.5

Parameters

CBC Results:	WBC, RBC, HB, HCT, MCV, MCH, MCHC, CHCM, RDW, HDW, CH, CHDW, PLT.
Differential Results (absolute and %):	NEUT, LYMPH, MONO, EOS, BASO, LUC (Large Unstained Cells).
Platelet Results:	PLT, MPV, PDW, PCT.
Reticulocyte Results:	% and # RETIC, MCVr, CHCMr, RDWr, HDWr, CHr, CHDWr**.
CSF assay results:	optional

Morphology results (User definable)

WBC:	Left Shift, Atypical Lymph, Blasts, BL-ABN, Immature Granulocytes, Myeloperoxidase Deficiency.
RBC:	NRBC, ANISO, MICRO, MACRO, HC VAR, HYPO, HYPER, RBC Fragments, RBC Ghosts, Platelet Clumps, Large Platelets.

Test Selectivity / Throughput

CBC	120 Samples/hr.
CBC/DIFF	120 Samples/hr.
CBC/DIFF	74 Samples/hr.
CBC/Retic	74 Samples/hr.
Retic	74 Samples/hr.

Sample Modes / Volumes

Automatic Closed Tube	157 µL.
Manual Closed Tube	157 µL.
Manual Open Tube	157 µL.

Weight and Dimensions

Analytical Module with Autosampler
(including reagents):

Weight	193 kg / 425 lbs
Height	86 cm / 33.8 in
Width	141 cm / 55.5 in
Depth	68 cm / 26.8 in

Analytical Module without Autosampler
(including Reagents):

Weight	163 kg / 360 lbs
Height	86 cm / 33.8 in
Width	81 cm / 31.9 in
Depth	68 cm / 26.8 in

Data Management

Data Base	10,000 Patient Storage Capacity Including Graphics.
Review and Edit Capability:	User Defined Windows User Defined Reports User Defined ranges based on Age and Sex for Normal Range, Panic, Rerun and Delta Check Criteria
Bi-Directional and Host Query Communication Protocols.
Extensive Quality Control:	3D Bar Graph Levy-Jennings Plot SDI Graphs Table Format
Remote QC.
ILQC Program.
Patient Moving Average.
Extensive On Line Documentation:	Context Sensitive Field Help Operations Manual Procedure Wizards Assistance Problem Solving Diagnostics Remote Diagnostics

Workstation Specifications

	Windows NT®. 15 Gigabyte Hard Disk Drive. 128 MB Memory. CD-RW. 17” Color Monitor. Full size Keyboard (Major Languages).

Physical Specifications

Electrical Power Requirements:	Dedicated Line Voltage Selectable for Single-Phase: 100 VAC (6 AMPS) – 240 VAC (3 AMPS) Frequency: 50/60 HZ
Temperature Requirements:	Operating: 18ºC – 32ºC Storage: -40ºC – +70ºC
Relative Humidity:	Operating: 15% – 80% (noncondensing) Heat Generation – less than 3000 BTU’s.
Waste Disposal:	Azide–free reagents drain into a waste container with automatic level-sensor shutoff Optional auto waste removal system

Auto Sampler Option

150 Sample Capacity:	15 Racks with 10 tube capacity
Compatible Tube Type:	Vacutainer®, Hemogard®, Monovette®, (Sarstedt 2.6 ml tubes require rack modification)
Bar Code Reader:	Up to 14 digits
Automatic discrimination of label codes:	Codabar Interleave 2 of 5 with and without check digit Code 39 Code128 EAN and JAN (8 and 13)

Other Specifications

	Windows NT®. Onboard analytical and wash reagents (1850 CBC/Diff tests). Automated Daily Maintenance – fully programmable.

*Specifications are subject to change
**Laboratory Use Only

ADVIA is a registered trademark and Unifluidics is atrademark of Bayer Healthcare LLC.
Windows NT is a registered trademark of Microsoft Corporation.
©2003 Bayer HealthCare LLC. All rights reserved.

Product specifications are subject to change without notice. The information is presented "as is" and may include technical inaccuracies or typographical errors.